Metadata-Version: 2.1
Name: abdesign
Version: 0.0.3
Summary: Antibody humanization framework
Home-page: https://github.com/SchubertLab/ABDesign
Author: Jannis Köckritz
Author-email: jannis.koeckritz@helmholtz-muenchen.de
License: UNKNOWN
Description: # ABDesign
        
        ## API
        
        The ABDesign API provides functions and data structures for dealing with Immunoglobulin sequences. It contains computational methods to 'humanize' an antibody by CDR-grafting.
        
        > **Note:** A local installation of ANARCI is needed for this tool. You can downlod ANARCI [here.](http://opig.stats.ox.ac.uk/webapps/newsabdab/sabpred/anarci/#download "ANARCI Download")
        
        ### IgObject
        Core data structure. All params are set on initialization, either by using create_annotation(), or manually.
        
        * seq *required*
        * chain_type
        * iso_type
        * species
        * annotation
        * regions
        
        * export_to_json()
        
        ### Humanization
        To 'humanize' a queried sequence, a human template sequence must be provided in form of an IgObject, too. It is also possible to indicate the wanted annotation types for the hybrid IgObject. By default, all annotation systems provided by this package are applied.
        
        * replace_cdr(ig_query:IgObject, ig_target:IgObject, annotation_types)
Platform: UNKNOWN
Classifier: Programming Language :: Python :: 3
Classifier: License :: OSI Approved :: MIT License
Classifier: Operating System :: MacOS :: MacOS X
Classifier: Operating System :: Unix
Requires-Python: >=3.6
Description-Content-Type: text/markdown
